Adrenal and Ovarian Steroids versus Cyproterone Acetate(CA) in Girls with Precocious Puberty(PP)

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Cyproterone acetate in treatment of precocious puberty.

Twenty-nine children (23 girls, 6 boys) with precocious puberty were treated with cyproterone acetate for various periods of time ranging from 6 months to 3 years 4 months. They received an oral dose ranging from 70-150 mg/m2 per day, or an intramuscular depot injection once a fortnight or once a month at a dose ranging from 107-230 mg/m2. Both forms of therapy were found to suppress the signs ...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1978

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197802000-00076